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. 2022 Sep 8;90(10):e00263-22. doi: 10.1128/iai.00263-22

FIG 7.

FIG 7

MroQ is important for S. aureus skin and soft tissue infection in Agr type I strains. (A) Representative images of skin abscesses at 96 h after infection with LAC (WT), ΔmroQ, ΔmroQ + mroQ, Δagr::tet, and Δagr::tet ΔmroQ strains. (B) Bacterial burden in skin abscesses of mice at 96 h after infection with LAC (WT) (n = 10), ΔmroQ (n = 10), ΔmroQ + mroQ (n = 10), Δagr::tet (n = 10), and Δagr::tet ΔmroQ (n = 10) strains. (C) Representative images of skin abscesses at 96 h after infection with SA502A (WT), ΔmroQ, ΔmroQ + mroQ, Δagr::tet, and Δagr::tet ΔmroQ strains. (D) Bacterial burden in skin abscesses of mice at 96 h after infection with SA502A (WT) (n = 10), ΔmroQ (n = 10), ΔmroQ + mroQ (n = 10), Δagr::tet (n = 10), and Δagr::tet ΔmroQ (n = 10) strains. (E) Representative images of skin abscesses at 96 h after infection with MW2 (WT), ΔmroQ, ΔmroQ + mroQ, Δagr::tet, and Δagr::tet ΔmroQ. (F) Bacterial burden in skin abscesses of mice at 96 h after infection with MW2 (WT) (n = 10), ΔmroQ (n = 10), ΔmroQ + mroQ (n = 10), Δagr::tet (n = 10), and Δagr::tet ΔmroQ (n = 10) strains. P values were determined by a nonparametric one-way ANOVA (Kruskal-Wallis test) with Dunn’s posttest. *, P < 0.05; **, P < 0.01; ***, P < 0.001.