Fig 2. Local LTB₄ concentration in the plantar tissue after the incision and pain assessment after local injection of LTB₄ in BLT1WT mice.

Quantitative analysis of LTB₄ concentration at the incisional site in BLT1WT mice was performed using LC-MS/MS. Data are expressed as pg of LTB₄ per mg of tissue and shown as means ± SEM (n = 6–7 per group). LTB₄ concentration increased significantly from baseline 3 hours and 1day after the incision. A one-way ANOVA with Bonferroni post hoc tests was used for statistical analysis. ***p < 0.001, **p < 0.01 vs. pre-incision.