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. 2022 Jun 29;13(1):287–295. doi: 10.1080/21541248.2022.2083895

Figure 2.

Figure 2.

MDS accurately detects KRAS cDNA mutants spiked into 293T genomic DNA. Frequency of single (detected) versus co-occurring (expected) mutations identified by MDS using a dilution series of KRAS cDNAs containing two different mutations engineered in KRAS exon 1 mixed with genomic DNA from 293T cells. Three biological replicates for MDS assay performed on the transcribed strand of KRAS exon 1 are show on the top and three biological replicates for MDS assay performed on the non-transcribed strand of KRAS exon 1 are show on the bottom.