Figure 1.

Distribution of LVEF and LVMD values in PLN p. Arg14del mutation carriers. The vertical black line represents the cut-off value for LVEF (45%), whereas the horizontal black line represents the cut-off value for LVMD (45 ms). According to these cut-off values, mutation carriers were classified into three subgroups: normal LV function (preserved LVEF and normal LVMD, in green), mechanical LV dysfunction (preserved LVEF and abnormal LVMD, in yellow) and overt LV dysfunction (reduced LVEF, in red). Mutation carriers who experienced sustained VA during follow-up are marked with a black dot. LV, left ventricular; LVEF, LV ejection fraction; LVMD, LV mechanical dispersion; VA, ventricular arrhythmia.