TABLE 3.

Laboratory and clinical findings for patients with IgA deficiency^a

Patient no.	Age (yr)	IgA level (mg/dl)	IgG level (mg/dl)	Gliadin IgG level (units)	EMG titer	TG-IgG OD	Biopsy findings	Clinical findings
1	3	<7	782	22	<1:5	0.11	Not done	Asymptomatic; the mother has CD
2	4	<7	1,140	26	<1:5	0.02	Not done	Upper respiratory infections
3	7	<7	1,440	2	<1:5	0.03	Not done	Type 1 diabetes
4	7	<7	1,680	18	<1:5	0.05	NVAb	Inflammatory bowel disease
5	13	<7	1,320	10	1:20	1.07	Unknown	Unknown
6	32	<7	1,432	1	1:5	0.05	Not done	Chronic bloating, gas
7	45	<7	1,810	13	<1:5	0.04	Unknown	Unknown
8	61	<7	346	1	<1:5	0.01	NVA	Diarrhea, malabsorption
9	67	<7	2,110	57	<1:5	0.12	Unknown	Unknown
10	2	12.5	618	19	<1:5	0.03	Not done	Chronic diarrhea
11	15	30.5	691	37	<1:5	0.03	Not done	Irritable bowel syndrome
12	77	34.5	1,500	1	<1:5	0.03	NVA	Diarrhea, colitis
13	47	46.7	411	1	<1:5	0.05	Not done	Diarrhea, anemia
14	16	50.5	964	5	<1:5	0.02	Not done	Diarrhea, weight loss
15	56	52.7	1,170	8	<1:5	0.01	Not done	Decreased vitamin D levels
16	19	54.3	560	13	<1:5	0.02	Not done	Irritable bowel syndrome
17	15	55.1	1,390	3	<1:5	0.18	Unknown	Unknown
18	48	55.3	854	7	<1:5	0.03	Not done	Family history of CD
19	15	55.4	770	6	<1:5	0.13	Unknown	Unknown
20	13	56.7	905	30	<1:5	0.04	Not done	Diarrhea, abdominal pain
21	68	57.4	690	11	<1:5	0.04	See note*c	Known CD on gluten-free diet; low urine calcium levels
22	47	58.6	2,230	3	<1:5	0.05	Unknown	Unknown
23	14	61.5	800	11	<1:5	0.03	Not done	Type I diabetes
24	13	67.1	609	32	<1:5	0.03	NVA	Poor weight gain
25	47	67.6	459	1	<1:5	0.01	Unknown	Unknown
26	13	67.9	1,050	4	<1:5	0.09d	Unknown	Unknown

^aBoldface type indicates abnormal results for IgG (decreased), gliadin IgG (increased), EMG (increased), or TG-IgG (increased). 

^bNVA, no villous atrophy. 

^cBiopsy showed villous atrophy when CD was diagnosed many years earlier; no biopsy was performed recently. 

^dThis patient's serum exhibited a slightly increased TG-IgA level (21 units).