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. 2022 Oct 18;9(2):103–114. doi: 10.36469/001c.37992

Table 4. PedsQL™ Score Study Outcomes.

Author (Year) Country PedsQL Score™
Marrie et al (2020)20 Canada Mean (SD) psychosocial HRQoL score on PedsQLTM at first measurement (patients with MS <18 y, healthy controls)
    76.13 (15.50) vs 79.57 (12.37)
    27.8% vs 16.3% with score >1 SD below mean of healthy participants
Mean (SD) physical HRQoL score on PedsQLTM at first measurement (patients with MS vs healthy controls)
    81.14 (19.49) vs 89.90 (9.59)
    30.6% vs 23.3% with score >1 SD below mean of healthy participants
16.7% patients with MS with physical function impaired at first HRQoL measurement
Florea et al (2020)30 France PedsQLTM inventory report <75 (%) among patients with MS ≤18 y
    Physical: 20
    Emotional: 50
    Social: 5
    School: 50
    Global: 40
Storm van’s Gravesande et al (2019)26 Germany, Austria Mean (SD) self-reported HRQoL scale scores (patients with RRMS 12-18 y vs age-matched healthy controls)
    Physical health: 74.62 (22.1) vs 86.67 (13.64)
    Emotional functioning: 63.35 (24.89) vs 71.9 (21.21)
    Social functioning: 88.73 (17.01) vs 91.96 (12.66)
    School functioning: 58.15 (24.74) vs 71.88 (19.14)
Storm van’s Gravesande et al (2019)27 Germany, Austria Mean (SD) self-reported HRQoL scale scores among patients with RRMS 12-18 y
    Physical health: 74.62 (22.1)
    Emotional functioning: 63.35 (24.89)
    Social functioning: 88.73 (17.01)
    School functioning: 58.15 (24.74)
    Total HRQoL scale: 71.81 (18.36)
Ghezzi et al (2017)29 Italy Mean (SD) PedsQLTM summary score at baseline, 52-wk follow-up among patients with RRMS 12-16 y
    Total scale score: 80.3 (13.5), 80.7 (13.9)
    Physical health: 81.3 (15.9), 81.9 (15.7)
    Psychosocial health: 79.7 (13.8), 80.1 (14.9)
Toussaint-Duyster et al (2018)28 Netherlands PedsQLTM-HRQoL functioning scores >1 SD below the mean among patients with MS 4-17 y (%)
    Total: 36
    Physical: 45
    Emotional: 18
    Social: 32
    School: 46
    Psychosocial: 46
Schwartz et al (2018)24 US, Canada Mean (SD) PedsQLTM among patients with MS 10-18 y
    Physical functioning: 80.17 (18.50)
    Emotional functioning: 68.03 (23.05)
    Social functioning: 83.18 (17.22)
    School functioning: 63.56 (18.50)
    Psychosocial health summary score: 71.59 (16.06)
Yeh et al 2017)25 US, Canada Mean PedsQLTM score for patients with MS 10-18 y in interventional control group, motivational interview group
    Physical functioning: Baseline 82.75, 81.88; 6-mo follow-up 75.13, 83.46
    Emotional functioning: Baseline 72.04, 70.20; 6-mo follow-up 65.60, 67.71
    Social functioning: Baseline 82.04, 85.20; 6-mo follow-up 79.60, 85.83
    School functioning: Baseline 66.11, 66.80; 6-mo follow-up 64.00, 66.88
3-mo follow-up data also included

Abbreviations: HRQoL, health-related quality of life; PedsQL™, Pediatric Quality of Life Measurement Model; RRMS, relapsing-remitting multiple sclerosis.

Control group data reported as applicable to outcome of interest.