Table 3.
Characteristics of microcephalic and non- microcephalic patients.
| Non-microcephalic patients | Microcephalic patients | p | |||||||
|---|---|---|---|---|---|---|---|---|---|
| N | Mean | SD | N | Mean | SD | ||||
| Median | IQR | Median | IQR | ||||||
| Total participants | 621 | 100% | 91 | 100% | |||||
| Mean age | 12.14 | 841 | 12.2 | 0.885 | n.s. | ||||
| Sex | |||||||||
| Female | 317 | 51.0% | 44 | 48.4% | n.s. | ||||
| Male | 304 | 49.0% | 47 | 51.6% | n.s. | ||||
| Health status | |||||||||
| Subjective health status (1 very good- 6 bad) | 1 | 1 | 1 | 1 | + | ||||
| Epilepsy | 6 | 1.0% | 7 | 7.7% | * | ||||
| Optic support | 199 | 32.0% | 44 | 48.4% | + | ||||
| Hearing support | 8 | 1.3% | 11 | 12.1% | * | ||||
| Walking aid | 4 | 0.6% | 7 | 7.7% | * | ||||
| Psychiatric comorbidity | 185 | 29.8% | 61 | 67.0% | * | ||||
| Gestational age | |||||||||
| Preterm | 94 | 15.1% | 16 | 17.6% | n.s. | ||||
| Term | 524 | 84.4% | 75 | 82.4% | n.s. | ||||
| Post-term | 3 | 0.5% | 0 | 0% | n.s. | ||||
| Syndromic disorders | 32 | 5.2% | 28 | 30.8% | * | ||||
| Alagille syndrome | 1 | 3.1% | - | - | |||||
| DiGeorge syndrome | 2 | 6.3% | 2 | 7.1% | |||||
| Goldenhar syndrome | 1 | 3.1% | 1 | 3.6% | |||||
| Trisomy 18 | – | – | 1 | 3.6% | |||||
| Trisomy 21 | 18 | 56.3% | 17 | 60.7% | |||||
| Noonan syndrome | – | – | 1 | 3.6% | |||||
| Williams syndrome | 2 | 6.3% | 1 | 3.6% | |||||
| Others | 8 | 25.0% | 5 | 17.9% | |||||
p *denotes significant difference compared to non-microcephalic p < 0.001, + denotes p < 0.05, n.s. = not significant.
For ordinal scaled variables, median and IQR were given accordingly (printed in italics).