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. 2022 Aug 20;46(11):2013–2020. doi: 10.1038/s41366-022-01212-1

Table 3.

MS development odds ratios according to high levels of serum VEGFb in basal study.

IDF criteria ATP-III criteria
OR (95%CI) p value OR (95%CI) p value
Model 1a
High_VEGFb vs Low VEGFb 0.65 (0.43–1.006) 0.053 0.45 (0.27–0.75) 0.002
Model 2b
High_VEGFb vs Low VEGFb 0.61 (0.39–0.96) 0.035 0.38 (0.23–0.65) <0,001
Model 3c
High_VEGFb vs Low VEGFb 0.65 (0.41–1.02) 0.066 0.41 (0.24–0.70) 0.001
Model 4d
High_VEGFb vs Low VEGFb 0.79 (0.47–1.31) 0.4 0.51 (0.29–0.93) 0.03

aOdds ratios calculated by logistic regression adjusted by sex, age and IMC.

bOdds ratios calculated by logistic regression adjusted by sex, age, waist circumference, systolic blood pressure, diastolic blood pressure, serum triglycerides, fasting glucose and HDL- cholesterol levels.

cOdds ratios calculated by logistic regression adjusted by the same variables than model 2 plus serum hs-CRP and physical activity (IPAQ categories).

dOdds ratios calculated by logistic regression adjusted by the same variables than model 3 plus an interaction term between VEGFb levels and physical activity (IPAQ categories).