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. 2022 Oct 20;12:17557. doi: 10.1038/s41598-022-22513-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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A representative case of type 1 cuticular drusen. A 57-year-old woman presented with type 1 cuticular drusen. (A) Color fundus photography showed numerous cuticular drusen. The cuticular drusen area was scanned using spectral-domain optical coherence tomography (SD-OCT) (arrow). (B) Fundus fluorescein angiography showing hyperfluorescent drusen. This can confirm the diagnosis of cuticular drusen. (C) In the SD-OCT image scanned on the site of the arrow in Photo (A), the cuticular drusen area is magnified to categorize the types of cuticular drusen. It can be diagnosed as a type 1 cuticular drusen in which shallow elevation of the retinal pigment epithelium is present in a spectralis domain optical coherence tomography image. (D) Retinal sensitivity using microperimetry is topographically presented in a composited image.