Table 1.
Patient characteristics.
| Patients (n = 346) | |
|---|---|
| Female, n (%) | 176 (50.9%) |
| NASH, n (%) | 244 (70.5%) |
| Age, years | 59 (22–84) |
| BMI, kg/m2 | 27.1 (17.6–45.2) |
| Hypertension, n (%) | 147 (42.5%) |
| Diabetes mellitus, n (%) | 162 (46.8%) |
| Hyperlipidemia, n (%) | 198 (57.2%) |
| PNPLA3, CC/CG/GG, n | 66/145/135 |
| HSD17B13, AA/AG/GG, n | 180/129/37 |
| Albumin, g/dL | 4.4 (3.5–5.3) |
| AST, IU/L | 42 (12–208) |
| ALT, IU/L | 55 (9–263) |
| GGT, IU/L | 59 (13–716) |
| Platelet count, × 103/μL | 209.5 (57–450) |
| Total cholesterol, mg/dL | 198 (95–347) |
| Triglycerides, mg/dL | 139 (18–923) |
| LDL cholesterol, mg/dL | 121 (36–259) |
| HDL cholesterol, mg/dL | 51 (21–103) |
| FPG, mg/dL | 109 (76–374) |
| HbA1c, % | 6.2 (4.8–11.5) |
| Type IV collagen 7 s, ng/mL | 4.9 (2.5–12.0) |
| Fibrosis stage, 0/1/2/3/4, n | 115/110/59/43/19 |
| Steatosis grade, 1/2/3, n | 102/186/58 |
| Inflammation grade, 0/1/2/3, n | 14/202/110/20 |
| Ballooning grade, 0/1/2, n | 101/149/96 |
BMI body mass index, AST aspartate aminotransferase, ALT alanine aminotransferase, GGT gamma-glutamyl transferase, LDL low-density lipoprotein, HDL high-density lipoprotein, FPG fasting plasma glucose.