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. 2022 Oct 20;12:17608. doi: 10.1038/s41598-022-22729-5

Table 4.

Interaction of genetic factor with diabetes mellitus and obesity on advanced fibrosis.

Interaction Variables p value OR (95% CI) S
DM Genetic risk
Negative Negative 1
Positive Negative 0.261 1.86 (0.63–5.52)
Negative Positive 0.009 3.57 (1.37–9.29)
Positive Positive 0.001 4.86 (1.88–12.56) 1.12
Obesity Genetic risk
Negative Negative 1
Positive Negative 0.095 3.86 (0.79–18.85)
Negative Positive 0.186 2.81 (0.61–13.03)
Positive Positive 0.005 8.31 (1.92–36.06) 1.57

CI confidence interval, OR odds ratio, DM diabetes mellitus, S Synergy Index.