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. 2022 Oct 20;12:17578. doi: 10.1038/s41598-022-22400-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Change in PGC-1α, PGC-1β and CDKN2A gene expression in brain tissues. (A) Fold change of PGC-1α in patients compared to controls, (B) fold change of PGC-1β in patients compared to controls, (C) fold change of CDKN2A in patients compared to controls, (D) 3D graph showing the relation between expression of PGC-1α, PGC-1β and CDKN2A in patients and controls. Data are presented as mean ± SE. Controls versus patients p < 0.05 = *, p < 0.005 = **, p < 0.0005 = ***; PD versus PDD/DLB, p < 0.05 = #, p < 0.005 = ##, p < 0.0005 = ###; PDD versus DLB, p < 0.05 = §, p < 0.005 = §§, p < 0.0005 = §§§.