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. 2022 Oct 20;12:17562. doi: 10.1038/s41598-022-21728-w

Table 2.

The number of transcripts sharing protein family domains with the bacterial koreenceine biosynthesis pathway.

The bacterial gene involved in Koreenceine synthesis Function predicted by Lozano et al.20 PFAM id PFAM description Number of Conium maculatum transcripts sharing PFAM domain
kecF Pyridoxalphosphate-dependent aminotransferase PF00202 Aminotransferase class-III 81
kecG Ketoreductase PF00106 Short-chain dehydrogenase 436
kecG Ketoreductase PF08659 KR domain 14
kecG Ketoreductase PF13561 Enoyl-(Acyl carrier protein) reductase 331
kecH NAD(P)H oxidoreductase PF00106 Short-chain dehydrogenase 436
kecH NAD(P)H oxidoreductase PF08659 KR domain 14
kecH NAD(P)H oxidoreductase PF13561 Enoyl-(Acyl carrier protein) reductase 331

As the plant pathway uses PKS type III, unlike the bacterial pathway, we have excluded the PKS genes and included only the polyketide accessory genes and transaminase in our analyses when comparing the bacterial genes with C. maculatum transcripts.