Table 1.
Demographics and clinical scores presented as a mean ± standard deviation (SD) (except for gender). R, responders; NR, non-responders; HC, healthy controls; HAMD, Hamilton Depression Rating Scale; BDI, Beck Depression Inventory (BDI) (Beck et al. 1961); STAI-T, Spielberger’s State-Trait Anxiety Inventory–Trait
| Responders (R) N = 21 |
Non-responders (NR) N = 13 |
Statistics for R vs NR (independent samples t-test, exc. chi-square for gender*) |
Healthy controls (HC) N = 31 |
Statistics for R vs NR vs HC (one-way ANOVA, exc. chi-square for gender*) |
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|---|---|---|---|---|---|---|---|---|---|
| p | t | df | p | F | df | ||||
| Age (years) | 30.4 ± 11.7 | 30.1 ± 10.1 | 0.939 | -0.077 | 32 | 30.3 ± 10.0 | 0.997 | 0.003 | 64 |
| Gender | 11F and 10 M | 8F and 5 M | 0.601 | 0.273* | 1 | 18F and 13 M | 0.858 | 0.306* | 2 |
| Age at onset (years) | 25.1 ± 8.3 | 25.2 ± 11.3 | 0.968 | 0.040 | 32 | NA | NA | NA | NA |
| Duration of current episode (months) | 5.9 ± 6.1 | 8.8 ± 8.7 | 0.276 | 1.108 | 32 | NA | NA | NA | NA |
| HAMD baseline | 23.3 ± 4.9 | 22.9 ± 4.0 | 0.823 | -0.226 | 32 | 0.4 ± 0.8 | < 0.0001 | 381.5 | 64 |
| HAMD at 6 weeks | 4.5 ± 3.8 | 17.4 ± 5.1 | < 0.0001 | 8.442 | 32 | NA | NA | NA | NA |
| BDI baseline | 31.6 ± 6.8 | 32.4 ± 5.5 | 0.735 | 0.341 | 32 | 0.8 ± 1.5 | < 0.0001 | 358.0 | 64 |
| BDI at 6 weeks | 9.2 ± 7.3 | 24.2 ± 10.6 | < 0.0001 | 4.899 | 32 | NA | NA | NA | NA |
| STAI-Trait anxiety at baseline | 60.0 ± 8.4 | 63.3 ± 10.3 | 0.321 | 1.009 | 32 | 29.2 ± 7.7 | < 0.0001 | 116.1 | 64 |
| STAI-Trait anxiety at 6 weeks | 46.1 ± 14.1 | 56.9 ± 11.3 | 0.026 | 2.335 | 32 | NA | NA | NA | NA |