Table 2.

Blood–brain partition coefficient (logBB) obtained from Eqs. 1–4 and probability of crossing the blood–brain barrier (AdmetSAR web tool)

	logBB				BBB crossing probability
	Equation 1	Equation 2	Equation 3	Equation 4
TP1	− 0.94	− 0.26	− 1.11	− 0.99	0.9614
TP4	− 0.54	− 0.23	− 0.03	0.11	0.9738
TP5	− 0.47	− 0.27	0.09	0.19	0.9735
TP6	− 0.33	− 0.28	0.23	0.24	0.9735
TP7	− 0.37	− 0.27	0.15	0.21	0.9735
TP8	− 0.38	− 0.27	0.25	0.29	0.9733
TP9	− 0.59	− 0.32	0.00	0.05	0.9733
TP10	− 0.39	− 0.21	0.22	0.22	0.9742