Table 4.

S. cerevisiae strains used in this study

Strain	Relevant genotype	Reference
CEN.PK 113-5D	MATa HIS3 LEU2 TRP1 ura3-52	(Entian and Kötter 2007)
CEN.PK 113-7D	MATa HIS3 LEU2 TRP1 URA3	(Entian and Kötter 2007)
IMX581	MATa HIS3 LEU2 TRP1 ura3-52 can1∆::cas9-natNT2	Mans et al. (2015)
IMX585	MATa HIS3 LEU2 TRP1 URA3 can1∆::cas9-natNT2	Mans et al. (2015)
IMK824	MATa HIS3 LEU2 TRP1 URA3 can1∆::cas9-natNT2 ura1∆	This study
IMI433	MATa HIS3 LEU2 TRP1 URA3 can1∆::cas9-natNT2 ura1∆::Aadho	This study
IMI434	MATa HIS3 LEU2 TRP1 URA3 can1∆::cas9-natNT2 ura1∆::Scdho	This study
IME410	MATa HIS3 LEU2 TRP1 ura3-52 pUDE737	This study
IME414	MATa HIS3 LEU2 TRP1 ura3-52 pUDE736	This study
IME426	MATa HIS3 LEU2 TRP1 ura3-52 pUD63	This study
IME664	MATa HIS3 LEU2 TRP1 URA3 can1∆::cas9-natNT2 ura1∆ pUDE737	This study
IME665	MATa HIS3 LEU2 TRP1 URA3 can1∆::cas9-natNT2 ura1∆ pUDE736	This study