Table 2.
Descriptive statistics for participants with patient-reported outcome data at Baseline and Week 7 for key EORTC domain and Spearman correlations between key EORTC domain scores and the Global Health Status item for change from Baseline to Week 7
| EORTC domain score | n, Missing (%), mean ± SD, min–max | r (p-value) | ||
|---|---|---|---|---|
| Baseline [n = 483] | Week 7 [n = 483] | Change from Baseline to Week 7 [n = 483] |
Between EORTC domain and Global Health Status for ∆ from Baseline to Week 7 | |
| EORTC QLQ-C30 Physical Functioning | 483 | 483 | 483 | 0.33 (<0.0001) |
| 0 (0.0) | 0 (0.0) | 0 (0.0) | ||
| 77.8 ± 18.4 | 74.9 ± 20.4 | −2.9 ± 16.5 | ||
| 6.7–100.0 | 6.7–100.0 | −60.0 to 60.0 | ||
| EORTC QLQ-LC13 Dyspnea | 482 | 482 | 482 | −0.29 (<0.0001) |
| 1 (0.2) | 1 (0.2) | 1 (0.2) | ||
| 24.9 ± 21.0 | 26.2 ± 21.2 | 1.4 ± 18.1 | ||
| 0.0–100.0 | 0.0–100.0 | −66.7 to 66.7 | ||
| EORTC QLQ-LC13 Coughing | 482 | 482 | 482 | −0.14 (0.0028) |
| 1 (0.2) | 1 (0.2) | 1 (0.2) | ||
| 34.7 ± 27.3 | 31.4 ± 26.6 | −3.3 ± 26.4 | ||
| 0.0–100.0 | 0.0–100.0 | −100.0 to 100.0 | ||
| EORTC QLQ-LC13 Pain in Chest | 482 | 482 | 482 | −0.20 (<0.0001) |
| 1 (0.2) | 1 (0.2) | 1 (0.2) | ||
| 17.7 ± 23.5 | 14.6 ± 22.0 | −3.1 ± 23.9 | ||
| 0.0 – 100.0 | 0.0–100.0 | −100.0 to 66.7 | ||
| EORTC Global Health Status | 482 | 482 | 482 | NA |
| 1 (0.2) | 1 (0.2) | 1 (0.2) | ||
| 66.0 ± 19.9 | 65.0 ± 19.9 | −1.0 ± 19.5 | ||
| 0.0–100.0 | 0.0–100.0 | −66.7 to 83.3 | ||
EORTC European Organisation for Research and Treatment of Cancer, min minimum, max maximum, QLQ-C30 30-item core instrument, QLQ-LC13 13-item lung cancer module, SD standard deviation, NA not applicable