This study corroborates the appropriateness of 10-point thresholds for identifying meaningful within-patient change on European Organisation for Research and Treatment of Cancer (EORTC) scores in lung cancer.

By accounting for the amount of change that is possible on each score, proposed thresholds for interpreting change on EORTC scores in lung cancer range from 11.11 to 33.33.

To enhance ease of interpretation, researchers should consider applying the thresholds proposed here for identifying individuals who have responded to treatment or who have experienced deterioration in future lung cancer studies.