Table 2.
Structural and visual function parameters.
| AQP4-IgG+ | MOG-IgG+ | MS | HC | AQP4-IgG+-nON versus MOG-IgG + -nON | AQP4-IgG+-nON versus MS-nON | AQP4-IgG+-nON versus HC | AQP4-IgG+-ON versus MOG-IgG + -ON | AQP4-ON versus MS-ON | AQP4-IgG+-ON versus HC | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| nON | ON | nON | ON | nON | ON | – | |||||||
| Mean (SD) | p-value | ||||||||||||
| HCVA [logMAR] | − 0.09 (0.11) |
0.33 (0.59) |
− 0.11 (0.15) |
− 0.10 (0.13) |
− 0.13 (0.11) |
− 0.004 (0.36) |
− 0.13 (0.09) |
0.46 | 0.07 | 0.21 | 0.004 | 0.013 | < 0.001 |
| LCVA [logMAR] |
0.29 (0.17) |
0.85 (0.68) |
0.25 (0.19) |
0.65 (0.70) |
0.31 (0.23) |
0.48 (0.34) |
0.26 (0.14) |
0.59 | 0.69 | 0.36 | 0.15 | 0.07 | < 0.001 |
| MD [dB] |
− 0.95 (2.36) |
− 9.76 (10.6) |
− 0.27 (0.85) |
− 6.10 (5.83) |
− 1.05 (1.41) |
− 2.78 (5.63) |
− 0.30 (1.05) |
0.26 | 0.30 | 0.24 | 0.59 | 0.08 | < 0.001 |
| pRNFL [µm] |
94.9 (11.5) |
59.5 (23.4) |
98.5 (13.0) |
51.7 (13.5) |
91.1 (11.9) |
74.4 (15.6) |
96.4 (10.1) |
0.49 | 0.11 | 0.57 | 0.39 | 0.01 | < 0.001 |
| GCIP [µm] |
65.6 (7.15) |
51.7 (9.95) |
69.2 (4.63) |
50.6 (7.84) |
66.6 (7.44) |
56.0 (7.22) |
68.7 (4.83) |
0.11 | 0.72 | 0.03 | 0.61 | 0.13 | < 0.001 |
| Inner rim volume [mm3] |
0.090 (0.015) |
0.090 (0.022) |
0.107 (0.024) |
0.096 (0.012) |
0.111 (0.018) |
0.098 (0.016) |
0.096 (0.021) |
0.06 | < 0.001 | 0.25 | 0.051 | 0.02 | 0.19 |
Test statistics from Mann–Whitney-U Test.
AQP4-IgG+aquaporin-4-IgG seropositive patients, MOG-IgG+myelin-oligodendrocyte-glycoprotein seropositive patients, MS multiple sclerosis, nON eyes without history of optic neuritis, ON eyes with history of optic neuritis, SD standard deviation, HCVA high contrast visual acuity, LCVA low contrast visual acuity, logMAR logarithm of minimum angle of resolution, MD mean deviation, pRNFL peripapillary retinal nerve fiber layer, GCIP combined ganglion cell and inner plexiform layer.
Significant values are in bold.