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. 2022 Oct 20;12:17593. doi: 10.1038/s41598-022-22536-y

Table 5.

Hepatic mRNA expressions of key enzymes involved in urea cycling, creatine and purine catabolism. Data are given as least square means and standard error (SE).

Parameter NP LP P value1
HMU LMU SE P value2 HMU LMU SE P value2 Diet Group Diet × Group
XDH 0.896b 1.205a 0.097 0.043 0.964ab 1.073ab 0.103 0.436 0.756 0.046 0.328
GAMT 0.909 1.114 0.075 0.063 1.049 0.954 0.071 0.347 0.892 0.461 0.048
GATM 0.866 1.221 0.128 0.075 1.055 1.040 0.136 0.934 0.977 0.209 0.172
ARG1 1.004 1.145* 0.100 0.328 1.078 0.895* 0.094 0.180 0.373 0.829 0.107
NOS2 1.060 0.931 0.136 0.510 1.112 1.116 0.128 0.983 0.380 0.642 0.621
UOX 1.091 1.119 0.139 0.889 1.044 1.030 0.139 0.939 0.617 0.961 0.877

a,bDifferent superscript letters within one row indicate P < 0.05 (Tukey-test).

*Same symbol within one row indicate P < 0.1 (Tukey-test).

XDH, xanthine dehydrogenase; GAMT, guanidinoacetate N-methyltransferase; GATM, glycine amidinotransferase; ARG1, arginase 1; NOS2, nitric oxide synthase; UOX, urate oxidase.

1P value from ANOVA analysis.

2P value from Tukey slice test.