Skip to main content
. 2021 Mar 17;111:6–26. doi: 10.1016/j.jhin.2021.03.007

Table V.

Intervention types and compliance outcomes

Study Year Type of intervention(s) No. of interventions Compliance at baseline Compliance post intervention (effect increase/decrease)
Aghdassi et al. [43] 2020 Education and training, reminder, infrastructural improvement, feedback 4 59% 61% (+2%) P=0.03
Apisarnthanarak et al. [55]c 2015 Education and training, infrastructural improvement 2 66% 84% (+18%) P=0.84, 0.02, 0.005
Benudis et al. [66] 2020 Reminders 1 Clear percentage data could not be extrapolated from the paper which reports that HH compliance improved by 1.3 percentage points per month during the intervention period, P=0.0005
Beyfus et al. [49] 2016 Reminders 1 HHOs only (dispenser volume). Average volume dispensed in stations with eyes was 279 cc vs 246 cc in stations without eyes, P=0.009
Chakravarthy et al. [41] 2015 Education and training, reminders, infrastructural improvement, feedback, leadership 5 37% 82% (+45%) P=0.0001
Chhapola and Brar [79] 2015 Education and training, reminders, feedback 3 46% 69% (+23%) P≤0.0001
Diefenbacher et al. [65] 2019 Feedback, leadership, teamwork 3 HHOs alone. HH dispenser usage almost doubled during the intervention, and increases were sustained during the post-intervention phase, P=0.004
Derde et al. [35] 2014 Education and training 1 52% 77% (+25%) P-value not stated
Derksen et al. [74] 2020 Reminders, infrastructural improvement 2 47% 95% (+48%) P<0.001
Donati et al. [85] 2020 Education and training, reminders, feedback, leadership 4 63% 77% (+14%) P=0.031
Ellison et al. [48] 2015 Reminders 1 26% 37% (+11%) P<0.001
Farhoudi et al. [88] 2016 Education and training, reminders, infrastructural improvement, feedback, leadership 5 30% 71% (+41%) P<0.001
Fouad and Eltaher. [71] 2020 Education and training, feedback 2 31% 46% (+15%) P<0.01
Fox et al. [81] 2015 Education and training, reminders, feedback 3 48% 75% (+27%) P-value not stated
Harrabi et al. [57] b 2017 Intervention not described in detail Intervention not described in detail 70% 77% (+7%) P-value not stated
Kai et al. [50] 2020 Education and training 1 6% 56% (+50%) P<0.0001
Khan and Nausheen [54] 2017 Feedback 1 15% 81% (+66%) P<0.0001
King et al. [75] 2016 Reminders 2 (sensory and visual cue are two separate reminders) 15% 47% (+32%) olfactory prime, P=0.0001; male eyes, P=0.038; female eyes, P=0.626
Kuruno et al. [72] 2017 Education and training, feedback 2 16% 57% (+41%) P<0.05
Labi et al. [40] 2019 Education and training, infrastructural improvement, leadershipa 2 29% 68% (+39%) P<0.0001
Larson et al. [63] 2018 Education and training, feedback, leadership, teamwork 4 HHOs alone. Increase in number of HH events in one of three sites, P=0.0003. Results for Site 1 were not significant, P=0.59
Laurikainen et al. [53] 2016 Feedback 1 HHOs alone. Post intervention showed increases in ABHR dispenser usage in one of three sites, P=0.0003
Lea et al. [70] 2016 Leadership 1 38% 67% (+29%) P-value not stated
Lee et al. [62]b 2020 Education and training, leadership, teamwork 3 49% 66% (+17%) P-value not stated
Lytsy et al. [36]b 2016 Education and training, feedback 2 78% 79% (+1%) P-value not stated
Marra et al. [73] 2014 Reminders, feedback, leadershipa 2 HHOs alone. ABHR dispenser usage higher in intervention units. P-values varied by study site, all were significant
Medeiros et al. [89] 2015 Education and training, reminders, infrastructural improvement, feedback, leadership 5 27% 58% (+31%) P=0.0001
Moller-Sorenson et al. [47] 2016 Reminders 1 66% 91% (+25%) P<0.0001
Mu et al. [82] 2016 Education and training, infrastructural improvement, feedback, leadership 4 38% 76% (+38%) P<0.0001
Mukherjee et al. [51] 2020 Education and training, feedback, leadership 3 34% 100% (+66%) P-value not stated
Muller et al. [68] 2014 Feedback 1 66% 68% (+2%) P-value not stated
Ng et al. [78]b 2019 Education and training, infrastructural improvement, leadership 3 64% 82% (+16%) P=0.01
Nobile et al. [3] 2018 Education and training, feedback, leadershipa 2 HHOs alone. Decrease in breaches of HH protocol during intervention period, P=0.000
Nour-Eldein and Ali Mohamed [59] 2016 Education and training 1 20% 50% (+30%) P<0.001
Nyamadzawo et al. [39] 2020 Education and training, infrastructural improvement 2 48% 68% (+20%) P<0.001
Pong et al. [64] 2018 Education and training, reminders, feedback, teamwork 4 25% 63% (+38%) P<0.0001
Reisinger et al. [44]c 2014 Reminders 1 34% on room entry, 52% on room exit 39% on entry into room, P=0.79; 57% on exit from room, P=0.54
Renaudin et al. [60]b 2017 Education and training 1 88% 77% (-11%) P-value not stated
Rodrigeuz et al. [87]b 2015 Education and training, reminders, infrastructural improvements, feedback, leadership 5 62% 76% (+14%) P<0.0001
Saharman et al. [84] 2019 Education and training, reminders, feedback, leadership 4 27% 77% (+50%) P<0.001
Santoaningsih et al. [77]b 2017 Education and training, leadership 2 16% 27% (+11%) P<0.001
Schmitz et al. [37] 2014 Education and training, reminders, infrastructural improvement, feedback, leadership 5 2% 12% (+10%) P<0.001
Sopirala et al. [12] 2014 Education and training, reminders, feedback, leadership 4 30% 93% (+63%) P=0.001
Staats [42] 2017 Reminders 1 HHOs alone. Total dispenser use increased by 62.02%, P<0.0001
Stevenson et al. [83] 2014 Education and training, reminders, infrastructural improvement, feedback 4 HHOs alone. HHOs increased by 20.1% compared with 3.1% in control group, baseline not specified, P=0.001
Stewardson et al. [61] 2016 Education and training, reminders, infrastructural improvement, feedback, leadership, teamwork 5 66% 74% (+8%) P<0.0001
Su et al. [86] 2015 Education and training, reminders, infrastructural improvement, feedback, leadership 5 52% 80% (+28%) P=0.004
Teesing et al. [90] 2020 Education and training, reminders, feedback, leadership, teamwork 5 12% 36% (+14%) P-value not stated
Tschudin-Sutter et al. [80] 2019 Education and training, reminders, feedback 3 HH baseline not clearly stated
van der Kooi et al. [58] 2018 Education and training 1 36% 58% (+22%) P<0.0001
Vander Weg et al. [67]b 2019 Reminders 1 56% 57% (+1%) P=0.14, P=0.06
Visnovsky et al. [69]c 2019 Infrastructural improvement (intervention involved reduction in contact precautions) 1 HH compliance net change could not be extrapolated. Data not significant for effect when personal protective equipment removed, P=0.07; or for change in intervention group, P=0.29
von Lengerke et al. [46] 2017 Education and training, feedback, leadershipa 2 54% 70% (+16%) P=0.005
von Lengerke et al. [45] 2019 Education and training, feedback, leadershipa 2 54% 70% (+16%) P=0.005
Wiedenmayer et al. [38] 2020 Education and training, reminders, infrastructural improvement, feedback, leadership 5 30% 56% (+26%) P<0.001
Xiong et al. [56] 2016 Education and training 1 Records increase in intervention group performance of proper HH technique, P=0.00. Percentage compliance data for HHOs not recorded
Yilmaz et al. [52]b 2016 Education and training, feedback 2 28% 73% (+45%) P<0.001
Mean HH compliance Mean baseline 41% Mean post intervention 67% (mean net effect +26%)

ABHR, alcohol-based hand rub; HH, hand hygiene; HHO, hand hygiene opportunity.

All percentage data have been rounded to the nearest integer. Studies that did not record compliance percentage data are marked as HHO alone. Where data could not be extrapolated from the studies, this is noted in the ‘Compliance post intervention’ column.

a

Leadership is alluded to in the study but not considered by this review to be part of the intervention. This is discussed further in the Results section under ‘Hand hygiene compliance interventions’.

b

Data were extrapolated from figures provided in the tables of these papers.

c

Study was excluded from mean calculations as the results failed to reach significance.