Table 3.

Outcomes of Adults Diagnosed with Acute Pulmonary Embolism in Primary Care, Stratified by Clinicians’ Initial Site-of-Care Decisions: Clinic Only Versus Referral to a Higher Level of Care

	Total cohort (n = 652)	Clinic only (n = 134)	Referral (n = 518)
			Discharged from ED to home (n = 196)	Initially hospitalized* (n = 322)
Outcomes, n (col. %; 95% CI)
7-d pulmonary embolism-related   hospitalization†	328 (50.3; 46.4–54.2)	4 (3.0; 0.8–7.5)	2 (1.0; 0.1–3.6)	322 (100)
30-d adverse outcomes
Venous thromboembolism   recurrence	4 (0.6; 0.2–1.6)	1 (0.7; 0–4.1)	0 (0; 0–1.9)	3 (0.9; 0.2–2.7)
Major bleed	1 (0.2; 0–0.9)	0 (0; 0–2.7)	0 (0; 0–1.9)	1 (0.3; 0–1.7)
All-cause mortality	3 (0.5; 0.1–1.3)	0 (0; 0–2.7)	0 (0; 0–1.9)	3 (0.9; 0.2–2.7)
Sum	8 (1.2; 0.5–2.4)	1 (0.7; 0–4.1)	0 (0; 0–1.9)	7 (2.2; 0.9–4.4)

ED emergency department

^*Seven of these 322 were directly hospitalized from primary care without ED evaluation

^†Note that 6 had a delayed hospitalization after initial outpatient management. We define “pulmonary embolism-related” in the Supplement and describe the 6 patients and their clinical courses in Supplement Table 4