Table 2.
Total follow-up (f/u) time, number and incidence rate of PDAC per 1,000 person-years (PY) and 95% CI (n=109,266).
| Total f/u time (years) | No. of PDAC | Incidence rate of PDAC/1000-PY (95% CI) |
Time to PDAC (days) (median, IQR) |
|
|---|---|---|---|---|
| Total | 224,573 | 319 | 1.4 (1.3, 1.6) | 141 (39, 406) |
| Age group | ||||
| 50–64 | 129,369 | 91 | 0.7 (0.6, 0.9) | 147 (32, 395) |
| 65–84 | 95,204 | 228 | 2.4 (2.1, 2.7) | 137.5 (40, 409) |
| Sex | ||||
| Female | 118,485 | 154 | 1.3 (1.1, 1.5) | 123.5 (35, 385) |
| Male | 106,088 | 165 | 1.6 (1.3, 1.8) | 157 (44, 415) |
| Race/ ethnicity | ||||
| Non-Hispanic white | 76,150 | 164 | 2.2 (1.8, 2.5) | 137.5 (40, 397) |
| African American | 32,105 | 40 | 1.2 (0.9, 1.7) | 114.5 (42, 292) |
| Asian/Pacific Islanders | 36,048 | 33 | 0.9 (0.6, 1.3) | 249 (42, 435) |
| Hispanic | 75,045 | 79 | 1.1 (0.8, 1.3) | 135 (35, 417) |
| HbA1c values on index date | ||||
| 6.5–6.9% | 171,833 | 173 | 1.0 (0.9, 1.2) | 157 (40, 444) |
| 7.0–7.4% | 23,087 | 51 | 2.2 (1.7, 2.9) | 134 (48, 359) |
| ≥7.5% | 29,653 | 95 | 3.2 (2.6, 3.9) | 105 (26, 307) |
| HbA1c change in 1y | ||||
| < 0.3 | 92,307 | 94 | 1.0 (0.8, 1.2) | 250.5 (48, 494) |
| ≥ 0.3 | 62,816 | 137 | 2.2 (1.8, 2.6) | 112 (32, 295) |
| None | 69,450 | 88 | 1.3 (1, 1.6) | 152 (44.5, 415.5) |
| HbA1c values in prior 6m | ||||
| ≥6.5% | 43,899 | 101 | 2.3 (1.9, 2.8) | 135 (46, 404) |
| <6.5% | 19,572 | 29 | 1.5 (1.0, 2.1) | 249 (68, 444) |
| None | 161,102 | 189 | 1.2 (1.0, 1.3) | 135 (34, 399) |
| HbA1c values in prior 18m | ||||
| ≥6.5% | 65,920 | 122 | 1.9 (1.5, 2.2) | 137.5 (38, 404) |
| <6.5% | 76,099 | 91 | 1.2 (1.0, 1.5) | 141 (31, 400) |
| None | 82,553 | 106 | 1.3 (1.1, 1.5) | 152 (48, 414) |