Table 5.
Histopathological outcomes of all specimens.
| All specimens | Resection specimen | FNA | |
|---|---|---|---|
| PanNET | 131 (89.1%)* | 106 (96.4%)* | 25 (67.6%) |
| Normal pancreas | 6 (4.1%) | 2 (1.8%) | 4 (10.8%) |
| PDAC | 7 (4.8%)*|^ | 2 (1.8%)* | 5 (13.5%)|^ |
| Other or not representative | 3 (2.0%) | 0 (0%) | 3 (8.1%) |
All tissues were collected indicating that patients could contribute multiple specimens; with regards to FNA, three patients had two biopsies of the same lesion. In one patient, the FNA was positive for a PanNET twice; in one, normal pancreatic tissue was followed by PanNET; and in the last patient, the biopsy was positive for PDAC twice. One patient had FNA of two lesions, so the 37 FNA results represent 34 lesions from 22 patients.
*In one patient, the tumor was a collision tumor consisting of a PDAC surrounded by multiple PanNETs.
|In one patient, a biopsy was initially positive for PDAC; revision of the specimen during follow-up changed the conclusion into a PanNET.
^In one patient with a PDAC-positive biopsy, the surgical resection specimen revealed a PanNET and no PDAC.
FNA, fine needle aspiration; PDAC, pancreatic ductal adenocarcinoma; PanNET, pancreatic neuroendocrine tumor.