TABLE 2.
SeDeM Parameters, indices, limit values and calculating factors.
| Incidence | Parameters | Limit value (v) | Factors applied to v | Radius (r) |
|---|---|---|---|---|
| Dimension | Bulk density (Da) | 0–1 g/ml | 10v | 0–10 |
| Tapped density (Dc) | 0–1 g/ml | 10v | 0–10 | |
| Compressibility | Inter-particle porosity (Ie) | 0–1.2 | 10v/1.2 | 0–10 |
| Carr’s index (IC) | 0–50 (%) | v/5 | 0–10 | |
| Cohesion index (Icd) | 0–200 (N) | v/20 | 0–10 | |
| Flowability/powder flow | Hausner’s ratio (IH) | 1–3 | 5 (3 - v) | 0–10 |
| Angle of repose (α) | 50–0 (°) | 10 - (v/5) | 0–10 | |
| Powder flow (tn) | 20–0 (s) | 10 - (v/2) | 0–10 | |
| Lubricity/Stability | Loss on drying (% HR) | 0–10 (%) | 10 - v | 0–10 |
| Hygroscopicity (% H) | 20–0 (%) | 10 - (v/2) | 0–10 | |
| Lubricity/dosage | Particle size (% Pf) | 50–0 (%) | 10 - (v/5) | 0–10 |
| Homogeneity index (Iθ) | 0–2 × 10–2 | 500v | 0–10 |