Table 3.
Univariate analysis of the predictive factors.
| Variable | Univariate Logistic Regression | ||||
|---|---|---|---|---|---|
| OR | CI | P | |||
| Sex | Women vs. Men | 0.55 | 0.42-0.73 | <0.001 | *** |
| Age | 1.03 | 1.02-1.04 | <0.001 | *** | |
| BMI | <25 vs. ≥25 kg/m2 | 0.93 | 0.74-1.16 | 0.51 | |
| Hypertension | No vs. yes | 1.30 | 0.90-1.86 | 0.16 | |
| Diabetes | No vs. yes | 1.26 | 0.73-2.18 | 0.41 | |
| Hyperthyroidism | No vs. yes | 2.13 | 0.43-10.60 | 0.36 | |
| The Echogenicity of the Thyroid Gland | Homogeneous vs. Heterogeneous | 1.28 | 1.01-1.64 | 0.05 | |
| Location | Upper vs. Lower | 1.11 | 0.84-1.46 | 0.48 | |
| Upper vs. Middle | 1.22 | 0.89-1.68 | 0.22 | ||
| Nodular Echogenicity | Hyperechoic/isoechoic vs. Marked hypoechoic | 2.38 | 0.69-8.20 | 0.17 | |
| Hyperechoic/isoechoic vs. Hypoechoic | 2.83 | 0.81-9.86 | 0.10 | ||
| Nodular Composition | Cystic and Solid vs. Solid | 4.78 | 1.31-17.46 | 0.02 | ** |
| Number of foci | 0.78 | 0.70-0.87 | <0.001 | *** | |
| Multifocality | Unifocal vs. Unilateral multifocal | 0.76 | 0.55-1.04 | 0.09 | |
| Unifocal vs. Bilateral multifocal | 0.62 | 0.48-0.80 | <0.001 | *** | |
| Maximum Tumor Diameter on Ultrasound | 0.20 | 0.15-0.26 | <0.001 | *** | |
| A/T | <1 vs. ≥1 | 1.14 | 0.91-1.42 | 0.26 | |
| Shape | Regular vs. Irregular | 0.85 | 0.68-1.05 | 0.14 | |
| Margins | Well-defined vs. Ill-defined | 1.19 | 0.94-1.51 | 0.14 | |
| Calcification | Absent vs. Present | 0.35 | 0.28-0.44 | <0.001 | *** |
| Capsule | Intact vs. Close to or invading | 0.44 | 0.32-0.61 | <0.001 | *** |
| Ultrasound-Reported Lymph Node Status | Negative vs. Suspicious | 0.34 | 0.26-0.44 | <0.001 | *** |
| TPO Antibody Level | <26.45 vs. ≥26.45 pmol/L | 1.66 | 1.25-2.19 | <0.001 | *** |
BMI, body mass index; A/T, anteroposterior diameter/ transverse diameter; TPO, thyroid peroxidase. Significance: ∗∗P < 0.05; ∗∗∗P < 0.01.