Figure 6.
The inhibitory effects of miR-30e on cell proliferation are mitigated by GLDC. (A) The expression of miR-30e was negatively correlated with PCNA expression in the same TNBC tissues. (B) High levels of miR-30e were associated with better overall survival. (C, D) Treatment with anti-miR-30e increased cell viability (C) * indicates p < 0.05 compared with anti-NC+siControl group, # indicates p < 0.05 compared with anti-miR-30e+siControl group and promoted BrdU incorporation. (D), which was attenuated by the knockdown of GLDC. (E, F): Restoration of GLDC depressed the regulatory effects of miR-30e on cell viability (E) * indicates p < 0.05 compared with NC+Vector group, # indicates p < 0.05 compared with miR-30e+Vector group and BrdU incorporation (F).