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. 2022 Oct 7;12:1010853. doi: 10.3389/fcimb.2022.1010853

Figure 3.

Figure 3

Alterations in the fecal microbiome of IBD patients compared to healthy controls. (A) Phylogenetic tree based on the microbiome distance between IBD patients and control subjects showing different clusters. (B) Shannon index representing alpha diversity of IBD (n = 14) and control subjects (n = 12). (C) Beta diversity analysis represented by multidimensional scaling (MDS) and pairwise Bray-Curtis distances (boxplots) between both groups. (D) Boxplots showing differentially abundant genera. (E) The top 20 significant genera were identified using random forest models, ranked by the index of accuracy and Gini. (F) Comparison of relative abundance of the genera Faecalibacterium and Blautia between control, ulcerative colitis (UC), and Crohn’s disease (CD) groups. The symbols (ns), (*), (**), and (***) indicate the significance values of P > 0.05 (not significant), P < 0.05, P < 0.01, and P < 0.001, respectively.