Table 5.
Effect of formulation compositions on the physico-chemical characteristics of developed TvT and TvP formulations.
| TvT formulations | Parameters | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| pH | Visible extraneous matter(g tablet-1) | Moisture content(%) | Disintegration time(min) | Tablet integrity | Density (g cm-3) | |||||||||
| TvT1 | 7.16 | 0.0046 | 7.55 | 22.50 | No broken tablets | 0.0017 | ||||||||
| TvT2 | 7.33 | 0.0044 | 10.07 | 24.00 | No broken tablets | 0.0016 | ||||||||
| TvT3 | 7.24 | 0.0082 | 9.77 | 26.50 | No broken tablets | 0.0017 | ||||||||
| TvT4 | 7.34 | 0.0056 | 9.97 | 23.50 | No broken tablets | 0.0017 | ||||||||
| TvT5 | 7.45 | 0.0062 | 9.31 | 25.00 | No broken tablets | 0.0016 | ||||||||
| TvT6 | 7.32 | 0.0083 | 9.84 | 26.50 | No broken tablets | 0.0017 | ||||||||
| TvT7 | 7.41 | 0.0055 | 9.76 | 23.50 | No broken tablets | 0.0016 | ||||||||
| TvT8 | 7.21 | 0.0043 | 9.48 | 26.00 | No broken tablets | 0.0015 | ||||||||
| TvT9 | 7.48 | 0.0070 | 9.88 | 24.50 | No broken tablets | 0.0018 | ||||||||
| TvP formulation | Parameters | |||||||||||||
| pH | Flowability |
Density
(g cm-3) |
% Retention of powder (mesh size wise) | |||||||||||
| BSS 5 | BSS16 |
BSS
30 |
BSS60 | BSS 100 | BSS 120 | BSS 240 | BSS 325 | |||||||
| TvP2 | 6.50 | Free-flowing | 0.732 | 0 | 1.1 | 4.4 | 14.6 | 1.9 | 3.6 | 41.9 | 0.2 | |||