Table 7.
Effects of associating cabergoline with ketoconazole in Cushing’s disease patients.
ID | Sex | Adenoma | Maximum daily (mg) dose of ketoconazole | Maximum weekly dose of cabergoline | Control | Other medications | Side effects | Outcome |
---|---|---|---|---|---|---|---|---|
7 | F | Macro | 1,000 | 3.5 mg | No | Temozolomide and pasireotide | Gastrointestinal effects | RDT |
9 | F | Normal | 1,000 | 3.5 mg | No | Mitotane | AI symptoms | Adrenalectomy |
10 | F | Macro | 1,200 | 3 mg | Yes | – | – | Medications maintained |
14 | F | Macro | 800 | 1.5 mg | No | – | Elevation of transaminases | RDT |
15 | F | Micro | 1,200 | 3 mg | No | Mitotane | – | RDT |
21 | F | Normal | 600 | 2 mg | Yes | – | Gastrointestinal symptoms | Adrenalectomy |
26 | F | Macro | 400 | 2 mg | No | – | – | RDT |
28 | M | Macro | 1,200 | 4.5 mg | No | Pasireotide | Hyperglycemia, hypogonadism, and hypokalemia | RDT |
AI, adrenal insufficiency; ND, no data; RDT, radiotherapy.