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. 2022 Oct 7;13:1017331. doi: 10.3389/fendo.2022.1017331

Table 7.

Effects of associating cabergoline with ketoconazole in Cushing’s disease patients.

ID Sex Adenoma Maximum daily (mg) dose of ketoconazole Maximum weekly dose of cabergoline Control Other medications Side effects Outcome
7 F Macro 1,000 3.5 mg No Temozolomide and pasireotide Gastrointestinal effects RDT
9 F Normal 1,000 3.5 mg No Mitotane AI symptoms Adrenalectomy
10 F Macro 1,200 3 mg Yes Medications maintained
14 F Macro 800 1.5 mg No Elevation of transaminases RDT
15 F Micro 1,200 3 mg No Mitotane RDT
21 F Normal 600 2 mg Yes Gastrointestinal symptoms Adrenalectomy
26 F Macro 400 2 mg No RDT
28 M Macro 1,200 4.5 mg No Pasireotide Hyperglycemia, hypogonadism, and hypokalemia RDT

AI, adrenal insufficiency; ND, no data; RDT, radiotherapy.