Table 2.
Characteristics of M1a CRLM patients who benefit from the surgery.
| Parameters | All surgery M1a CRLM patientsn = 881 (%) |
Non-beneficial n = 173 (%) |
Beneficial n = 708 (%) |
p-Value |
|---|---|---|---|---|
| Age | <0.001 | |||
| <50 | 214 (24.3) | 17 (9.8) | 197 (27.8) | |
| 50 ≤ X < 70 | 483 (54.8) | 77 (44.5) | 406 (57.4) | |
| ≥70 | 184 (20.9) | 79 (45.7) | 105 (14.8) | |
| Sex | 0.099 | |||
| Female | 414 (47.0) | 91 (52.6) | 323 (45.6) | |
| Male | 467 (53.0) | 82 (47.4) | 385 (54.4) | |
| Size | 0.007 | |||
| ≤3 cm | 146 (16.6) | 22 (12.7) | 124 (17.5) | |
| 3 < X ≤ 5 cm | 376 (42.7) | 68 (39.3) | 308 (43.5) | |
| 5 < X ≤ 7 cm | 227 (25.7) | 43 (24.9) | 184 (26.0) | |
| >7 cm | 132 (15.0) | 40 (23.1) | 92 (13.0) | |
| Race | 0.544 | |||
| Black | 135 (15.3) | 21 (12.2) | 114 (16.1) | |
| White | 654 (74.2) | 135 (78.0) | 519 (73.3) | |
| Other | 91 (10.4) | 17 (9.8) | 74 (10.5) | |
| Unknown | 1 (0.1) | 0 (0.0) | 1 (0.1) | |
| Grade | <0.001 | |||
| I | 26 (3.0) | 4 (2.3) | 22 (3.1) | |
| II | 646 (73.3) | 102 (59.0) | 544 (76.8) | |
| III | 140 (15.9) | 51 (29.5) | 89 (12.6) | |
| IV | 38 (4.3) | 13 (7.5) | 25 (3.5) | |
| Unknown | 31 (3.5) | 3 (1.7) | 28 (4.0) | |
| Histology | 0.05 | |||
| Adenocarcinoma | 753 (85.5) | 156 (90.2) | 597 (84.3) | |
| Other | 128 (14.5) | 17 (9.8) | 111 (15.7) | |
| T stage | <0.001 | |||
| T1 | 20 (2.3) | 3 (1.7) | 17 (2.4) | |
| T2 | 34 (3.8) | 2 (1.2) | 32 (4.5) | |
| T3 | 582 (66.1) | 97 (56.1) | 485 (68.5) | |
| T4 | 245 (27.8) | 71 (41.0) | 174 (24.6) | |
| N stage | <0.001 | |||
| N0 | 167 (19.0) | 17 (9.8) | 150 (21.2) | |
| N1 | 390 (44.3) | 68 (39.3) | 322 (45.5) | |
| N2 | 324 (36.8) | 88 (50.9) | 236 (33.3) | |
| Neoadjuvant chemotherapy | <0.001 | |||
| No | 126 (14.3) | 75 (43.4) | 51 (7.2) | |
| Yes | 755 (85.7) | 98 (56.6) | 657 (92.8) | |
| Marital status | <0.001 | |||
| Married | 528 (59.9) | 95 (54.9) | 433 (61.2) | |
| Separated or divorced | 85 (9.6) | 17 (9.8) | 68 (9.6) | |
| Single | 169 (19.2) | 25 (14.5) | 144 (20.3) | |
| Widowed | 72 (8.2) | 30 (17.3) | 42 (5.9) | |
| Unknown | 27 (3.1) | 6 (3.5) | 21 (3.0) | |
| CEA | 0.109 | |||
| Negative/normal | 209 (23.7) | 33 (19.1) | 176 (24.9) | |
| Positive/elevated | 672 (76.3) | 140 (80.9) | 532 (75.1) | |
| Primary tumor position | <0.001 | |||
| Left colon | 385 (43.7) | 49 (28.3) | 336 (47.5) | |
| Right colon | 380 (43.1) | 108 (62.4) | 272 (38.4) | |
| Rectum | 116 (13.2) | 16 (9.3) | 100 (14.1) |
CRLM, colorectal cancer with liver metastasis; CEA, carcinoembryonic antigen.
p < 0.05 means the result is statically significant.