Table 7.
IC50 values of the plant extracts examined on affinity purified GSTs (unit: mg GAE/g dry plant)
| Examined plant | hGSTP1-1 | Erythrocyte GST | Placenta GST |
|---|---|---|---|
| Curcuma longa | 4.54±0.67d | 7.30±0.90d | 8.80±0.92f |
| Zingiber officinale | 5.30±0.55d | 3.60±0.49e | 11.30±0.85e |
| Alpinia galanga | 0.82±0.07efg | 11.80±0.96b | 10.80±1.00e |
| Tamarindus indica | 1.12±0.26ef | 1.80±0.18f | 0.75±0.06i |
| Cinnamomum verum | 0.66±0.08efg | 12.78±0.85b | 12.18±0.40e |
| Syzygium aromaticum | 4.52±0.68d | NI | 7.20±0.60f |
| Apium graveolens | 4.80±0.63d | 10.40±0.96c | 7.40±0.45f |
| Punica granatum | 1.67±0.35e | 10.50±0.85c | 4.74±0.52g |
| Lepidium sativum | 5.36±0.50d | 6.84±0.55d | 7.23±0.88f |
| Raphanus sativus | 14.60±0.88a | NI | 19.30±0.95c |
| Eruca sativa | 12.60±1.00b | NI | 30.40±1.90b |
| Brassica rapa var. rapa | NI | 12.45±0.83b | 16.30±1.20d |
| Brassica oleracea | 11.80±1.10b | 16.00±1.00a | 34.80±1.70a |
| Brassica oleracea var. botrytis | NI | 9.90±0.70c | 16.75±0.96d |
| Hibiscus cannabinus | 6.63±0.84c | NI | NI |
| Hibiscus sabdariffa | 0.48±0.06fg | NI | 4.32±0.76g |
| Gossypium arboreum | 1.59±0.18e | 6.80±0.74d | 2.70±0.42h |
Values are presented as mean±SD.
Means with different letters (a-i) within the same column are significantly different at P<0.05.
IC50, the quantity of phenolic extract in GAE per gram of dry plant that inhibits enzyme activity by 50%; GAE, gallic acid equivalent; GST, glutathione transferase; NI, no inhibition (inhibition of GST activity could not be detected under our experiment conditions).