| Abstract P191 – Table 1. Clinical characteristics and TP‐DNA detection of included participants. Data are median [IQR], n (%), or n/N (%). | |||||
|---|---|---|---|---|---|
| Early syphilis (n = 145) | Primary syphilis (n = 14) | Secondary syphilis (n = 52) | Early latent syphilis (n = 79) | No early syphilis (n = 101) | |
| Age, years [IQR] | 36 [32 to 43] | 33 [30 to 43] | 33 [29 to 41] | 38 [34 to 44] | 33 [30 to 40] |
| MSM | 138 (99%) | 12 (92%) | 52 (100%) | 74 (99%) | 88 (97%) |
| >5 sexual partners in past 3 months | 18 (15%) | 2 (17%) | 10 (23%) | 6 (9%) | 6 (7%) |
| HIV‐positive | 134 (92%) | 12 (86%) | 46 (88%) | 76 (96%) | 62 (61%) |
| CD4 count, cells per μL | 619 [490 to 811] | 661 [530 to 823] | 641 [461 to 806] | 605 [503 to 794] | 578 [423 to 798] |
| On ART | 130/134 (97%) | 12/12 (100%) | 43/46 (93%) | 75/76 (99%) | 59/62 (95%) |
| HIV‐negative | 11 (8%) | 2 (14%) | 6 (12%) | 3 (4%) | 39 (39%) |
| On PrEP | 2/11 (18%) | 1/2 (50%) | 1/6 (17%) | 0/3 (0%) | 24/39 (62%) |
| Not on PrEP | 9/11 (82%) | 1/2 (50%) | 5/6 (83%) | 3/3 (100%) | 15/39 (38%) |
| RPR [IQR] | 128 [64 to 256] | 256 [64 to 256] | 256 [128 to 512] | 128 [32 to 256] | − |
| TP‐DNA positivity | |||||
| Oral rinse | 60 (41%) | 7 (50%) | 35 (67%) | 18 (23%) | 4 (4%) |
| Rectal swab | 40 (28%) | 4 (29%) | 26 (50%) | 10 (13%) | 1 (1%) |
| Urethral swab | 25 (17%) | 4 (29%) | 16 (31%) | 5 (6%) | 0 (0%) |
| Any sample | 71 (49%) | 9 (64%) | 38 (73%) | 24 (30%) | 4 (4%) |
| Ct value of PCR test | |||||
| Oral rinse | 31.78 [29.68 to 33.76] | 31.43 [30.14 to 32.85] | 31.24 [29.41 to 33.40] | 32.74 [32.01 to 33.80] | 33.70 [‐] |
| Rectal swab | 30.91 [27.90 to 33.84] | 32.47 [‐] | 30.79 [28.05 to 33.70] | 31.00 [27.23 to 34.60] | 37.93 [‐] |
| Urethral swab | 35.53 [33.51 to 36.99] | 34.62 [‐] | 34.94 [33.47‐37.02] | 35.93 | − |
Ct, cycle threshold; PrEP, pre‐exposure prophylaxis; RPR, rapid plasma reagin; TP‐DNA, Treponema pallidum DNA.