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. 2022 Oct 21;25(Suppl 6):e26009. doi: 10.1002/jia2.26009
Abstract P228 – Table 1. Participants included for each virological outcome and multivariate analysis of factors associated with viral blip, low‐level viraemia, virological failure and virological suppression. Models were adjusted for gender, age, year of ART initiation, HIV transmission route, ethnicity, HBV and HCV status, body mass index, smoking status, origin region, prior AIDS diagnosis, baseline HIV‐1 RNA, baseline CD4+ T‐cell count and initial ART classes.
Virological outcome Viral blip Low‐level viraemia Virological failure Virological suppression week 48 Virological suppression week 96
N included 2977 2977 3116 3055 2435
N with endpoint 448 113 162 2767 2262
% (95% CI) N/A N/A N/A 90.6 (89.5 to 91.6) 92.9 (91.9 to 93.9)
K‐M % at 12 months (95% CI) 10.9 (7.9 to 13.9) 3.2 (1.5 to 4.9) 4.7 (2.7 to 6.7) N/A N/A
Multivariate analysis Adjusted HR (95% CI), p‐value Adjusted HR (95% CI) p‐value Adjusted HR (95% CI) p‐value Adjusted OR (95% CI) p‐value Adjusted OR (95% CI) p‐value
HIV viral load, HIV‐1 RNA copies/mL
10 000 or under 0.52 (0.36 to 0.75), <0.001 0.45 (0.17 to 1.18), 0.10 0.70 (0.44 to 1.11), 0.13 1.41 (0.91 to 2.20), 0.13 1.18 (0.69 to 2.00), 0.55
10 001 to 100 000 1.0 (Ref) 1.0 (Ref) 1.0 (Ref) 1.0 (Ref) 1.0 (Ref)
>100 000 1.94 (1.55 to 2.42), <0.001 2.54 (1.58 to 4.07), <0.001 0.90 (0.61 to 1.32), 0.58 0.51 (0.37 to 0.70), <0.001 0.57 (0.38 to 0.84), 0.004
CD4+ T‐cell count, cells/μL
200 or under 2.84 (2.07 to 3.89), <0.001 7.87 (3.40 to 18.20), <0.001 2.94 (1.78 to 4.87), <0.001 0.42 (0.28 to 0.62), <0.001 0.40 (0.24 to 0.66), <0.001
201 to 350 2.07 (1.51 to 2.82), <0.001 5.13 (2.19 to 11.98), <0.001 1.02 (0.58 to 1.79), 0.95 0.63 (0.41 to 0.95), 0.03 0.57 (0.34 to 0.93), 0.02
351 to 500 1.33 (0.96 to 1.85), 0.09 3.13 (1.29 to 7.60), 0.01 1.34 (0.82 to 2.20), 0.25 0.93 (0.60 to 1.44), 0.75 1.35 (0.76 to 2.39), 0.31
>500 1.0 (Ref) 1.0 (Ref) 1.0 (Ref) 1.0 (Ref) 1.0 (Ref)

K‐M, Kaplan‐Meier; N, number of participants; N/A, not applicable.