| Abstract P236 – Table 1. Summary of patient characteristics at ICU admission. | ||||
|---|---|---|---|---|
| Characteristic, n (%) or median (interquartile range) | Overall n=207 | Not diagnosed late n=149 | Diagnosed late n=149 | p‐value |
| Demographic factors | ||||
| Age (years) | 46 (38‐53) | 46 (40‐54) | 44 (36‐52) | 0.11 |
| Male (sex at birth) | 148 (71.5%) | 110 (73.8%) | 38 (65.5%) | 0.23 |
| Clinical factors | ||||
| Acute Physiology and Chronic Health Evaluation II score | 19 (14‐25) | 19 (13‐25) | 21 (14‐26) | 0.28 |
| Advanced HIVa | 138 (67.3%) | 83 (56.5%) | 55 (94.8%) | <0.001 |
| Undetectable (viral load ≤50 copies/mL) | 90 (45.0%) | 85 (58.2%) | 5 (9.3%) | <0.001 |
| CD4+ T‐cell count <350 cells/mm3 at admission | 164 (80.4%) | 106 (72.6%) | 58 (100.0%) | <0.001 |
| Receipt of combination antiretroviral therapy (cART)b | 147 (73.5%) | 129 (88.4%) | 18 (33.3%) | <0.001 |
| Primary diagnosis at admission category | ||||
| Cardiovascular | 7 (3.4%) | 6 (4.0%) | 1 (1.7%) | 0.14 |
| Gastrointestinal | 23 (11.1%) | 18 (12.1%) | 5 (8.6%) | |
| Infection | 27 (13.0%) | 18 (12.1%) | 9 (15.5%) | |
| Lower respiratory tract infection | 65 (31.4%) | 43 (28.9%) | 22 (37.9%) | |
| Neurological | 20 (9.7%) | 12 (8.1%) | 8 (13.8%) | |
| Oncological/Haematological | 18 (8.7%) | 11 (7.4%) | 7 (12.1%) | |
| Renal | 12 (5.8%) | 10 (6.7%) | 2 (3.4%) | |
| Other | 35 (16.9%) | 31 (20.8%) | 4 (6.9%) | |
aCD4+ T‐cell count <200 cells/mm and/or an AIDS‐defining illness at admission;
bpatients were considered to be receiving cART if they had (1) data on cART start date pre‐dating ICU admission; or (2) a VL <1000 copies/mL at ICU admission but no cART date, as it was considered unlikely these patients exhibiting viraemic control were not on any form of cART.