Abstract P248 – Table 1. Demographic and clinical characteristics of the study population. | |||
---|---|---|---|
LP‐PLWH (n = 20) | HCWs (n = 20) | p‐value LP‐PLWH vs HCWsa | |
Age, years, median (IQR) | 57 (47 to 62) | 55 (45 to 61) | 0.3500 |
Sex, n (%) | 0.1908 | ||
Male | 15 (75) | 10 (50) | |
Female | 5 (25) | 10 (50) | |
Ethnicity, n (%) | 0.1264 | ||
Caucasian | 15 (75) | 20 (100) | |
Latin‐American | 3 (15) | 0 (0) | |
Afro‐American | 1 (5) | 0 (0) | |
African | 1 (5) | 0 (0) | |
Comorbidities, n (%) | |||
Hypertension | 5 (25) | 2 (10) | 0.4075 |
Chronic heart disease | 2 (10) | 0 (0) | 0.4872 |
Myocardial infarction | 1 (5) | 0 (0) | >0.9999 |
Peripheral vascular disease | 1 (5) | 0 (0) | >0.9999 |
Chronic pulmonary disease | 2 (10) | 2 (10) | >0.9999 |
Chronic kidney disease | 2 (10) | 1 (5) | >0.9999 |
Liver disease | 3 (15) | 0 (0) | 0.2308 |
Diabetes | 3 (15) | 0 (0) | 0.2308 |
Charlson comorbidity index,b median (IQR) | 2 (0 to 4) | 1 (0 to 2) | 0.1153 |
Epidemiology, n (%) | |||
MSM | 8 (40) | ||
IDU | 2 (10) | ||
Other | 10 (50) | ||
Viro‐immunological parameters, median (IQR) | |||
CD4 nadir, cells/μL | 67 (32 to 215) | ||
HIV‐RNA zenith, copies/mL | 60 816 (22 402 to 242 511) | ||
Current % CD4 | 25 (12 to 30) | ||
Current CD4, cells/μL | 404 (192 to 615) | ||
Current % CD8 | 46 (35 to 60) | ||
Current CD8, cells/μL | 809 (590 to 1008) | ||
Current CD4/CD8 ratio | 0.57 (0.20 to 0.87) | ||
Current HIV‐RNA, copies/mL | <20 | ||
Previous AIDS diagnosis, n (%) | 8 (40) | ||
Current cART regimen, n (%) | |||
INSTI‐based triple | 11 (55) | ||
INSTI‐based dual | 6 (30) | ||
NNRTI‐based triple | 3 (15) | ||
Duration of cART, years, median (IQR) | 12 (6 to 17) |
cART, combination antiretroviral therapy; HCWs, healthcare workers; IDU, injective drugs use; INSTI, integrase strand transfer inhibitor; IQR, interquartile range; LP‐PLWH, late presenter people living with HIV.
aStatistical analyses: Mann‐Whitney U test, Fisher exact test, Chi‐square test, as appropriate;
bage‐adjusted.