| Abstract P259 – Table 1. Logistic regression analysis to assess the relationship between sociodemographic, clinical variables, and disease progression in 1118 patients infected by SARS‐CoV‐2. | ||||
|---|---|---|---|---|
| Variables | Univariate | Analysis | Multivariate | Analysis |
| OR (95% CI) | p‐value | OR (95% CI) | p‐value | |
| Age | 1.03 (1.02 to 1.04) | <0.0001 | 1.04 (1.02 to 1.05) | <0.0001 |
| Males | 1.10 (0.86 to 1.42) | 0.44 | − | − |
| BMI >30 kg/m2 | 1.24 (0.93 to 1.66) | 0.14 | − | − |
| CKD | 1.24 (0.88 to 1.76) | 0.22 | − | − |
| Immunodeficiency | 0.89 (0.64 to 1.26) | 0.53 | − | − |
| Decompensated diabetes | 1.61 (1.11 to 2.33) | 0.01 | 1.03 (0.59 to 1.81) | 0.91 |
| Chronic liver disease | 1.40 (0.86 to 2.28) | 0.17 | − | − |
| Chronic respiratory disease | 1.69 (1.24 to 2.28) | 0.001 | 1.73 (1.11 to 2.69) | 0.02 |
| Neurological disorders | 1.52 (1.12 to 2.05) | 0.006 | 1.42 (0.93 to 2.16) | 0.10 |
| Oncological disease | 0.72 (0.51 to 1.02) | 0.06 | − | − |
| Haematological tumours | 1.61 (0.99 to 2.63) | 0.06 | 2.82 (1.41 to 5.65) | 0.003 |
| Cardiovascular diseases | 1.22 (0.95 to 1.58) | 0.12 | − | − |
| Number of comorbidities | 1.20 (1.09 to 1.31) | <0.0001 | − | − |
| CCI | 1.09 (1.04 to 1.14) | <0.001 | − | − |
| 4C‐score | 1.36 (1.29 to 1.43) | <0.0001 | − | − |
| Vaccine (at least two doses) | 0.18 (0.13 to 0.24) | <0.0001 | 0.22 (0.15 to 0.33) | <0.0001 |
| At least one symptom | 3.80 (2.34 to 6.19) | <0.0001 | − | − |
| Fever | 1.92 (1.49 to 2.47) | <0.0001 | 2.20 (1.53 to 3.15) | <0.0001 |
| Dyspnoea | 16.49 (11.95 to 22.76) | <0.0001 | 13.24 (8.99 to 19.50) | <0.0001 |
| Any antiviral | 0.11 (0.08 to 0.16) | <0.0001 | − | − |
| Molnupiravir | 0.14 (0.09 to 0.21) | <0.0001 | 0.13 (0.08 to 0.21) | <0.0001 |
| Nirmatrelvir/ritonavir | − | − | − | − |
| Remdesivir | 0.36 (0.15 to 0.86) | 0.02 | 0.18 (0.06 to 0.52) | 0.002 |
| Any monoclonal antibodies | 0.35 (0.24 to 0.52) | <0.0001 | − | − |
| Sotrovimab | 0.27 (0.14 to 0.52) | <0.0001 | 0.37 (0.16 to 0.84) | 0.02 |
| Casirivimab/imdevimab | 0.49 (0.32 to 0.75) | <0.0001 | 0.50 (0.28 to 0.89) | 0.02 |