Abstract P065 – Table 1. Main characteristics at enrolment by difficult‐to‐treat group.
Characteristics	Difficult to treat (n = 320)	Not difficult to treat (N = 7741)	p‐value	Total (n = 8061)
Females, n (%)	61 (19.1%)	1412 (18.2%)	0.709	1473 (18.3%)
Mode of HIV transmission, n (%)
IDU	22 (6.9%)	464 (6.1%)	0.075	486 (6.1%)
Homosexual contacts	137 (43.2%)	3774 (49.4%)		3911 (49.2%)
Heterosexual contacts	141 (44.1%)	2895 (37.4%)		3036 (37.7%)
Other/unknown	17 (5.4%)	503 (6.6%)		520 (6.5%)
Not Italian nationality, n (%)	97 (30.3%)	4171 (53.9%)	<0.001	4268 (52.9%)
HBsAg, n (%)			0.824
Negative	254 (79.4%)	6177 (79.8%)		6431 (79.8%)
Positive	1 (0.3%)	13 (0.2%)		14 (0.2%)
Not tested	65 (20.3%)	1551 (20.0%)		1616 (20.0%)
HCVAb, n (%)			0.002
Negative	230 (71.9%)	5774 (74.6%)		6004 (74.5%)
Positive	33 (10.3%)	438 (5.7%)		471 (5.8%)
Not tested	57 (17.8%)	1529 (19.8%)		1586 (19.7%)
Calendar year of baseline, median (IQR)	2014 (2013 to 2016)	2016 (2015 to 2018)	<0.001	2016 (2015 to 2018)
2008 to 2012	76 (23.8%)	542 (7.0%)		618 (7.7%)
2012 to 2016	193 (60.3%)	3344 (43.2%)		3537 (43.9%)
2017+	51 (15.9%)	3855 (49.8%)		3906 (48.5%)
Age, years, median (IQR)	43 (36 to 50)	39 (31 to 49)	<0.001	40 (31 to 49)
CD4 count, cells/mmc, median (IQR)	305 (105 to 473)	355 (167 to 534)		353 (163 to 532)
CD4 count nadir, cells/mmc, median (IQR)	111 (38.4%)	2057 (28.7%)	<0.001	2168 (29.1%)
AIDS diagnosis, n (%)	55 (17.2%)	763 (9.9%)	<0.001	818 (10.1%)
Viral load, log10 copies/mL, median (IQR)	4.93 (4.34 to 5.42)	4.72 (4.11 to 5.30)	0.001	4.73 (4.12 to 5.31)
Time from HIV diagnosis to date of starting ART, months, median (IQR)	1 (1 to 12)	1 (1 to 6)	0.186	1 (1 to 6)
Anchor drug started, n (%)			<0.001
NNRTI (DOR, RPV)	37 (11.6%)	1469 (19.0%)		1506 (18.7%)
PI (DRV/r)	149 (46.6%)	1568 (20.3%)		1717 (21.3%)
INSTI (RAL, EVG, DTG, BIC)	134 (41.9%)	4704 (60.8%)		4838 (60.0%)