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. 2022 Oct 21;25(Suppl 6):e26009. doi: 10.1002/jia2.26009
Abstract P066 – Table 1. Baseline characteristics of experienced patients in study.
Variables at enrolment Doravirine n = 128 mean SD or n (%) or median (IQR) Rilpivirine n = 331 mean SD or n (%) or median (IQR) p
Age, years 53.6±12.4 42.3±9.3 <0.0001
Sex, M 91 (71.1%) 237 (71.6%) 0.91
BMI, kg/m2 26.2±5.5 24.4±3.8 0.0002
Weight, kg 77.3±17.6 81.7±14.3 0.0007
Caucasian 117 (91.4%) 304 (91.8%) 0.88
Risk factor for HIV acquisition: sexual 89 (69.5%) 244 (73.7%) 0.16
Risk factor for HIV acquisition: IDU 24 (18.8%) 66 (19.9%) 0.16
Risk factor for HIV acquisition: other/ND 15 (11.7%) 21 (6.3%) 0.16
HBV coinfection (n = 102/321) 8 (7.8%) 20 (6.2%) 0.57
HCV coinfection (n = 107/329) 26 (24.3%) 76 (23.1%) 0.80
Detectable HIV‐RNA 16 (12.5%) 50 (15.1%) 0.48
Previous ART: PI 29 (22.7%) 152 (45.9%) <0.0001
Previous ART: INSTI 62 (48.4%) 17 (5.1%) <0.0001
Previous ART: NNRTI 47 (36.7%) 151 (45.6%) 0.08
CD4, cells/mm3 685 (493 to 955) 624 (443 to 820) 0.02
Total cholesterol, mg/dL 198±45 189±42 0.06
HDL‐cholesterol, mg/dL 51±15 48±16 0.08
LDL‐cholesterol, mg/dL 118±38 112±38 0.12
Triglycerides, mg/dL 114 (85 to 153) 120 (85 to 172) 0.56
On lipid‐lowering drugs 25 (19.5%) 29 (8.8%) 0.001
AST, UI/dL 21 (18 to 29) 24 (19 to 31) 0.008
ALT, UI/dL 24 (17 to 32) 28 (21 to 42) 0.0007