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. 2022 Oct 21;25(Suppl 6):e26009. doi: 10.1002/jia2.26009
Abstract P122 – Table 1. Characteristics of the 14 participants with loss of virological suppression by week 48.
P Age Gender/ethnicity cART directly prior to baseline RAMs prior to baseline VL at baseline (copies/mL) Number of viral blips prior to LVS (copies/mL) Time to LVS (weeks) VL at time of LVS (copies/mL) RAMs at LVS
1 51 M/C DRV/c/FTC/TAF NDA 101 Once; 168 36 218 NDA
2 34 F/SSA FTC/TAF + NVP NDA <50 None 48 397 NRTI: 67N, 70R, 184V
3 27 M/SSA DTG/ABC/3TC NDA 15 300 None 48 1188 None
4 22 M/SSA Naïve None <50 None 48 588 000 NDA
5 33 F/SSA DRV/c/FTC/TAF None 1080 None 48 21 000 NDA
6 46 F/C DTG/ABC/3TC NDA 12 600 None 16 418 None
7 45 M/SSA DRV/c/FTC/TAF None <50 None 27 385 NDA
8 55 F/SSA ABC/3TC + DRV/r NRTI: 184V INSTI: 66A, 92G <50 None 32 578 NDA
9 51 M/SSA Naïve None 5152 None 17 2154 None
10 55 M/SSA DTG + FTC/TAF None <50 Once; 77 37 457 None
11 31 M/C Naïve None 30 233 None 42 11 130 NDA
12 52 M/C DTG + FTC/TAF None <50 None 48 22 700 None
13 34 M/SSA DRV/c/FTC/TAF None <50 None 48 89 200 None
14 42 M/SSA Naïve None 932 Once; 182 48 836 NRTI: 184V INSTI: 263K/R

ABC/3TC, abacavir/lamivudine; C, Caucasian; cART, combined antiretroviral therapy; DRV/c, darunavir/cobicistat; DRV/r, darunavir/ritonavir; DTG, dolutegravir; F, female; FTC/TAF, emtricitabine/tenofovir alafenamide; INSTI, integrase strand transfer inhibitor; LVS, loss of virological suppression; M, male; NDA, no data available; NRTI, nucleoside/nucleotide reverse transcriptase inhibitor; NVP, nevirapine; P, patient; RAMs, resistance‐associated mutations; SSA, black sub‐Saharan African; VL, viral load.