| Abstract P151 – Table 1. Results of linear mixed models adjusted by age, sex, country of birth, prior AIDS‐defining conditions, CD4+ cell count, HIV‐RNA viral load, HCV antibodies, HBsAg, type of ART regimen according to anchor drug, and NRTI backbone. | ||||
|---|---|---|---|---|
| Weight mean (SE), kg | Baseline | 96 weeks | Increase | p |
| ZC3H4 rs3810291 | 0.007 | |||
| GG | 72.22 (70.43 to 74.02) | 76.43 (74.47 to 78.40) | 4.21 (3.12 to 5.30) | |
| AA/AG | 72.71 (71.98 to 73.45) | 75.35 (74.54 to 76.16) | 2.64 (2.27 to 3.02) | |
| BCDIN3D/FAIM2 rs7138803 | 0.019 | |||
| GG | 72.11 (71.16 to 73.06) | 75.43 (74.36 to 76.49) | 3.32 (2.76 to 3.88) | |
| AG/AA | 73.11 (72.13 to 74.08) | 75.59 (74.54 to 76.65) | 2.49 (2.02 to 2.95) | |
| BMI mean (95% CI), kg/m2 | Baseline | 96 weeks | Increase | p |
| ZC3H4 rs3810291 | 0.009 | |||
| GG | 24.01 (23.50 to 24.52) | 25.40 (24.83 to 25.98) | 1.39 (1.03 to 1.76 ) | |
| AA/AG | 24.20 (23.99 to 24.42) | 25.08 (24.85 to 25.32) | 0.88 (0.76 to 1.01) | |
| BCDIN3D/FAIM2 rs7138803 | 0.016 | |||
| GG | 24.07 (23.79 to 24.34) | 25.18 (24.87 to 25.49) | 1.11 (0.93 to 1.30) | |
| AG/AA | 24.26 (23.98 to 24.55) | 25.09 (24.78 to 25.40) | 0.82 (0.67 to 0.98) | |
BCDIN3D, BCDIN3 domain containing RNA methyltransferase; FAIM2, Fas apoptotic inhibitory molecule 2; ZC3H4, zinc finger CCCH‐type containing 4.