Abstract P158 – Table 1. Difference in change from baseline in metabolic, liver and quality of life parameters for the maraviroc + OBT versus OBT group with bootstrapped 95% confidence intervals. | ||||
---|---|---|---|---|
Measure | Week | Number of participants | Difference between groups in change from baseline | 95% confidence interval |
BMI, kg/m2 | 48 | 45 | −0.2 | −1.0 to 0.6 |
96 | 45 | −0.2 | −0.8 to 0.4 | |
Waist circumference, cm | 48 | 43 | 2.7 | −5.1 to 11 |
96 | 42 | 1.3 | −7.3 to 9.9 | |
CD4 cell count, cells/mm3 | 48 | 45 | 70 | −35 to 175 |
96 | 44 | −47 | −135 to 41 | |
Fasting glucose, mmol/L | 48 | 44 | −0.1 | −0.8 to 0.7 |
96 | 42 | 0.8 | −0.4 to 2.1 | |
HbA1c, mmol/mol | 48 | 45 | −2.3 | −6.6 to 2.1 |
96 | 45 | 2.5 | −3.0 to 8.0 | |
AST, U/L | 48 | 43 | −0.5 | −7.2 to 6.1 |
96 | 38 | 7.0 | −3.4 to 17 | |
ALT, U/L | 48 | 44 | −5.7 | −22 to 10 |
96 | 45 | 0.5 | −19 to 20 | |
Fasting triglycerides, mmol/L | 48 | 44 | 0.7 | −0.1 to 1.4 |
96 | 46 | −0.2 | −1.0 to 0.6 | |
Fasting LDL, mmol/L | 48 | 40 | 0 | −0.5 to 0.4 |
96 | 41 | 0 | −0.4 to 0.5 | |
Fasting HDL, mmol/L | 48 | 44 | 0 | −0.2 to 0.2 |
96 | 46 | 0.1 | −0.1 to 0.3 | |
Fasting HDL: total cholesterol ratio | 48 | 44 | 0.3 | −0.6 to 1.1 |
96 | 46 | −0.3 | −1.0 to 0.4 | |
Fasting total cholesterol, mmol/L | 48 | 44 | 0.1 | −0.4 to 0.6 |
96 | 46 | 0.1 | −0.4 to 0.7 | |
Fibroscan median liver stiffness, kPa | 48 | 43 | −1.7 | −3.8 to 0.4 |
96 | 41 | −0.2 | −2.0 to 1.6 | |
Fibroscan CAP score, dB/m | 48 | 41 | −15 | −56 to 25 |
96 | 39 | −5.8 | −41 to 30 | |
ELF score | 48 | 43 | 0.3 | 0 to 0.6 |
96 | 42 | 0.1 | −0.3 to 0.4 | |
Chronic Liver Disease Questionnaire for NAFLD | 48 | 45 | −0.3 | −1.0 to 0.4 |
96 | 44 | −0.5 | −1.3 to 0.2 |