| Abstract P178 – Table 1. Characteristics of PLWHIV according to PLR ratio tertile. | |||||
|---|---|---|---|---|---|
| Characteristics at starting ART | T1 (n = 3083) | T2 (n = 3085) | T3 (n = 3080) | p‐value | Total |
| Female, n (%) | 463 (15%) | 681 (22.1%) | 978 (31.8%) | <0.001 | 2122 (22.9%) |
| Mode of HIV transmission | <0.001 | ||||
| PWID | 597 (19.4%) | 436 (14.1%) | 387 (12.6%) | 1420 (15.4%) | |
| MSM | 1388 (45.0%) | 1390 (45.1%) | 1039 (33.7%) | 3817 (41.3%) | |
| Heterosexual contacts | 952 (30.9%) | 1114 (36.1%) | 1444 (46.9%) | 3510 (38.0%) | |
| Other/unknown | 146 (4.7%) | 145 (4.7%) | 210 (6.8%) | 501 (5.4%) | |
| Not Italian | 763 (24.7%) | 934 (30.3%) | 1150 (37.3%) | 0.001 | 2847 (30.8%) |
| AIDS diagnosis, n (%) | 150 (4.9%) | 165 (5.3%) | 668 (21.7%) | <0.001 | 983 (10.6%) |
| CVD diagnosis, n (%) | 23 (0.7%) | 19 (0.6%) | 29 (0.9%) | 0.337 | 71 (0.8%) |
| HBsAg, n (%) | 0.009 | ||||
| Negative | 2595 (84.2%) | 2579 (83.6%) | 2630 (85.4%) | 7804 (84.4%) | |
| Positive | 28 (0.9%) | 25 (0.8%) | 8 (0.3%) | 61 (0.7%) | |
| Not tested | 460 (14.9%) | 481 (15.6%) | 442 (14.4%) | 1383 (15.0%) | |
| HCV‐Ab, n (%) | <0.001 | ||||
| Negative | 2029 (65.8%) | 2204 (71.4%) | 2205 (71.6%) | 6438 (69.6%) | |
| Positive | 642 (20.8%) | 441 (14.3%) | 400 (13.0%) | 1483 (16.0%) | |
| Not tested | 412 (13.4%) | 440 (14.3%) | 475 (15.4%) | 1327 (14.3%) | |
| Hepatitis co‐infection, n (%) | <0.001 | ||||
| No | 1914 (62.1%) | 2075 (67.3%) | 2139 (69.4%) | 6128 (66.3%) | |
| Yes | 660 (21.4%) | 460 (14.9%) | 405 (13.1%) | 1525 (16.5%) | |
| Not tested | 509 (16.5%) | 550 (17.8%) | 536 (17.4%) | 1595 (17.2%) | |
| Calendar year of starting ART, median (IQR) | 2012 (2003 to 2016) | 2013 (2005 to 2016) | 2013 (2006 to 2017) | 2013 (2004 to 2016) | |
| Age, median (IQR) | 38 (31 to 46) | 37 (31 to 45) | 39 (33 to 47) | <0.001 | 38 (32 to 46) |
| CD4 count cells/mmc, median (IQR) | 404 (276 to 579) | 370 (254 to 505) | 195 (54 to 337) | <0.001 | 330 (184 to 479) |
| CD4 count nadir cells/mmc, median (IQR) | 383 (260 to 536) | 351 (240 to 476) | 186 (51 to 321) | <0.001 | 312 (174 to 452) |
| CD8 count cells/mmc, median (IQR) | 1270 (920 to 1706) | 899 (703 to 1153) | 559 (376 to 766) | <0.001 | 866 (590 to 1243) |
| CD4 count <200/mmc, n (%) | 436 (14.2%) | 530 (17.2%) | 1552 (51.1%) | <0.001 | 2518 (27.4%) |
| Months from HIV diagnosis, median (IQR) | 13 (2 to 60) | 6 (1 to 44) | 2 (1 to 21) | <0.001 | 4 (1 to 43) |
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