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. 2022 Oct 10;70(41):13200–13211. doi: 10.1021/acs.jafc.2c03143

Figure 1.

Figure 1

(A) Systolic blood pressure (SBP), (B) diastolic blood pressure (DBP), (C) heart rate in beats per minute (BPM), (D) the percentage of heart weight with respect to total body weight, (E) total heart lipid content, and (F) heart triglyceride (TG) content. SBP, DBP, and heart rate were measured at 5 months of age; heart weight, lipid content, and TG were measured after sacrifice (at 6 months of age). Results are expressed as the mean ± SEM of six to eight animals per group. C, offspring of control dams; CR, offspring of dams subjected to calorie restriction during the first 12 days of pregnancy; CRP, CR rats supplemented with high-esterified pectin between days 21 and 180 of life. SD, standard diet; HS, high-sucrose diet (supplemented between days 135 and 180 of life). Statistics: two-way ANOVA was performed to analyze the effects of Treatment (T) and Diet (D), with LSD post hoc analysis (A ≠ B). In case of a significant interaction (T×D), one-way ANOVA was performed, with LSD post hoc analysis, splitting individuals with standard diet (a ≠ b) and HS diet (x ≠ y). Specific differences between individual groups were assessed by Mann–Whitney U test (p < 0.05): *HS versus SD, $CR or CRP group versus C group (same diet). n.s., non-significant.