Heart mRNA
expression levels of genes coding for natriuretic peptides
A (Nppa) (A), B (Nppb) (B), C (Nppc) (C), myocardin (Myocd) (D), and myostatin
(Mstn) (E) at 6 months of age. PBMC expression levels
of Nppa at 4 (F) and 6 months (G) and of Mstn at 6 months of age (H). Results are expressed as a
percentage of the mean value of the control group, mean ± SEM
of 6 to 10 animals per group. C, offspring of control dams; CR, offspring
of dams subjected to calorie restriction during the first 12 days
of pregnancy; CRP, CR rats supplemented with high-esterified pectin
between days 21 and 180. SD, standard diet; HS, high-sucrose diet
(supplemented between days 135 and 180 of life). Statistics: ANOVA
and post hoc as explained in Figure 1 legend, A ≠ B, x ≠ y, Mann–Whitney U test (p < 0.05): *HS versus SD, $CR or CRP group versus C group (same diet), #HS
versus SD at the p < 0.1 level. n.s., non-significant.