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. 2020 Nov 25;1(1):ltaa008. doi: 10.1093/immadv/ltaa008

Figure 4.

Figure 4.

Vitamin D3 supplementation increases the accumulation of T cells at the site of VZV challenge. (A) RNAseq analysis of 3 mm biopsies collected from normal and VZV-injected skin (48 hours post-injection) pre- and post-vitamin D. The top 30 genes upregulated in VZV injected skin as compared to normal skin before post-Vitamin D3 (n = 16). (B) VZV-specific module and (C) T cell specific module in VZV-injected skin pre- and post-vitamin D3 supplementation separated based upon improvement in VZV score change of <2 (white; n = 9) and change ≥2 (red; n = 7). Paired data were analysed using a Wilcoxon-matched paired test and unpaired data with Mann–Whitney test. *P < 0.05; **P < 0.01.