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Summary of the functional findings from lung cancer GWAS loci at 5p15.33, 6p21 (MHC) and 6p22.1. (A) Summarized findings around genes TERT and CLPTM1L. (B) Conditional fine-mapping analyses on the MHC region at 6p21. (C) Regulatory mechanisms of rs17079281 on DCBLD1 expression and its functional consequences. Lung cancer risk-associated alleles are shaded in red and protective alleles in blue.
