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. 2022 Oct 21;10:75. doi: 10.1186/s40364-022-00423-y

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Immune signatures of low- and high-risk groups of CLL patients. A The infiltration of 22 types of immune cells in the low-risk group. B The infiltration of 22 types of immune cells in the high-risk group. C Correlations between immune cells in low-risk group. D Correlations between immune cells in high-risk group. E Differential expression of immune cells in low- and high-risk groups. F The stromal score, immune score and ESTIMATE score in high-risk group were lower than those in low-risk group. G Differential expression of immune checkpoint in low- and high-risk groups. H The heatmap of immune function analysis in low- and high-risk groups. (^*p < 0.05, ^**p < 0.01, ^***p < 0.001)