Table 4.

Final set of benefit and harm outcomes deemed to be of critical or important for guideline development and decision-making

Outcome	Consideration of the benefits/harms associated with the preventive health care intervention	Priority
All-cause mortality	• Potential benefit (reduction in) • Potential harm (increase in)	Critical
Hospitalization	• Potential benefit (reduction in) • Potential harm (increase in)	Critical
Non-serious (i.e., not requiring hospitalization and not causing death) adverse drug reactions including those related to withdrawal or stopping medication	• Potential benefit (reduction in) • Potential harm (increase in)	Critical
Quality of life	• Potential benefit (increase in) • Potential harm (reduction in)	Important
Emergency department visits	• Potential benefit (reduction in) • Potential harm (increase in)	Important
Injurious falls	• Potential benefit (reduction in) • Potential harm (increase in)	Important
Medical visits	• Potential benefit (reduction in) • Potential harm (increase in)	Important
Number of medications (and number of pills)	• Potential benefit only (reduction in)	Important