Table 2.

Variables Associated With a Faster Rate of Retinal Nerve Fiber Layer Thinning

	Univariable Analysis			Multivariable Analysis
	Beta	95% CI	P-Value	Beta	95% CI	P-Value
Age, per 1 y older	0.003	−0.001, 0.008	0.170
Female sex	−0.064	−0.204, 0.075	0.364
Highest IOP during the initial 6 mo, per 1 mm Hg higher	−0.057	−0.068, −0.045	<0.001	−0.050	−0.063, −0.037	<0.001
Glaucoma surgery during the initial 6 mo	−0.445	−0.626, −0.265	<0.001	−0.005	−0.198, 0.188	0.957
Mean LCCI, per 1 unit larger	−0.060	−0.084, −0.037	<0.001	−0.043	−0.065, −0.020	<0.001
Global CT, per 1 µm thicker	0.001	0.000, 0.003	0.061	0.001	0.000, 0.003	0.018
VF MD, per 1 dB higher	−0.004	−0.015, 0.008	0.545
VF PSD, per 1 dB higher	0.009	−0.008, 0.025	0.300
AXL, per 1 mm longer	−0.010	−0.056, 0.035	0.653
CCT, per 1 µm thicker	−0.002	−0.004, 0.001	0.060	0.000	−0.002, 0.001	0.674

CI, confidence interval; IOP, intraocular pressure; LCCI, lamina cribrosa curve index; CT, choroidal thickness; VF, visual field; MD, mean deviation; PSD, pattern standard deviation; AXL, axial length; CCT, central corneal thickness.

Significant P values are in bold.